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Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair
Stem cell-based therapies with clinical applications require millions of cells. Therefore, repeated subculture is essential for cellular expansion, which is often complicated by replicative senescence. Cellular senescence contributes to reduced stem cell regenerative potential as it inhibits stem ce...
Autores principales: | Park, Ji Hye, Kim, Hyeok, Moon, Hyung Ryong, Park, Bong-Woo, Park, Jae-Hyun, Sim, Woo-Sup, Kim, Jin-Ju, Lim, Hye Ji, Kim, Yeon-Ju, Ji, Seung Taek, Jang, Woong Bi, Rethineswaran, Vinoth Kumar, Van, Le Thi Hong, Giang, Ly Thanh Truong, Yun, Jisoo, Ha, Jong Seong, Ban, Kiwon, Chung, Hae Young, Baek, Sang Hong, Park, Hun-Jun, Kwon, Sang-Mo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492872/ https://www.ncbi.nlm.nih.gov/pubmed/34584195 http://dx.doi.org/10.1038/s12276-021-00676-x |
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