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A human antibody against human endothelin receptor type A that exhibits antitumor potency
Endothelin receptor A (ET(A)), a class A G-protein-coupled receptor (GPCR), is involved in the progression and metastasis of colorectal, breast, lung, ovarian, and prostate cancer. We overexpressed and purified human endothelin receptor type A in Escherichia coli and reconstituted it with lipid and...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492878/ https://www.ncbi.nlm.nih.gov/pubmed/34588605 http://dx.doi.org/10.1038/s12276-021-00678-9 |