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A human antibody against human endothelin receptor type A that exhibits antitumor potency

Endothelin receptor A (ET(A)), a class A G-protein-coupled receptor (GPCR), is involved in the progression and metastasis of colorectal, breast, lung, ovarian, and prostate cancer. We overexpressed and purified human endothelin receptor type A in Escherichia coli and reconstituted it with lipid and...

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Detalles Bibliográficos
Autores principales: Ju, Man-Seok, Ahn, Hye-Mi, Han, Seong-Gu, Ko, Sanghwan, Na, Jung-Hyun, Jo, Migyeong, Lim, Chung Su, Ko, Byoung Joon, Yu, Yeon Gyu, Lee, Won-Kyu, Kim, Youn-Jae, Jung, Sang Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492878/
https://www.ncbi.nlm.nih.gov/pubmed/34588605
http://dx.doi.org/10.1038/s12276-021-00678-9