A potent bispecific nanobody protects hACE2 mice against SARS-CoV-2 infection via intranasal administration

The dramatically expanding coronavirus disease 2019 (COVID-19) needs multiple effective countermeasures. Neutralizing nanobodies (Nbs) are a potential therapeutic strategy for treating COVID-19. Here, we characterize several receptor binding domain (RBD)-specific Nbs isolated from an Nb library deri...

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Detalles Bibliográficos
Autores principales: Wu, Xilin, Cheng, Lin, Fu, Ming, Huang, Bilian, Zhu, Linjing, Xu, Shijie, Shi, Haixia, Zhang, Doudou, Yuan, Huanyun, Nawaz, Waqas, Yang, Ping, Hu, Qinxue, Liu, Yalan, Wu, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492916/
https://www.ncbi.nlm.nih.gov/pubmed/34644535
http://dx.doi.org/10.1016/j.celrep.2021.109869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8492916/
https://www.ncbi.nlm.nih.gov/pubmed/34644535
http://dx.doi.org/10.1016/j.celrep.2021.109869

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