Ibrutinib reduces neutrophil infiltration, preserves neural tissue and enhances locomotor recovery in mouse contusion model of spinal cord injury

Following acute spinal cord injury (SCI), excessive recruitment of neutrophils can result in inflammation, neural tissue loss and exacerbation of neurological outcomes. Ibrutinib is a bruton’s tyrosine kinase inhibitor in innate immune cells such as the neutrophils that diminishes their activation a...

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Detalles Bibliográficos
Autores principales: Torabi, Somayyeh, Anjamrooz, Seyed Hadi, Zeraatpisheh, Zahra, Aligholi, Hadi, Azari, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Anatomists 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493027/
https://www.ncbi.nlm.nih.gov/pubmed/34031271
http://dx.doi.org/10.5115/acb.20.299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493027/
https://www.ncbi.nlm.nih.gov/pubmed/34031271
http://dx.doi.org/10.5115/acb.20.299

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