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Berberine Potentiates Insulin Secretion and Prevents β-cell Dysfunction Through the miR-204/SIRT1 Signaling Pathway

Pancreatic β-cell dysfunction is a key link during the progression of type 2 diabetes (T2DM), and SIRT1 participates in the regulation of various physiological activities of islet β-cells. However, as a key link in signal transduction, it is not clear how SIRT1 is regulated. By TargetScan prediction...

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Detalles Bibliográficos
Autores principales: Lv, Xiaoyan, Zhao, Yali, Yang, Xuehan, Han, Hao, Ge, Yue, Zhang, Meishuang, Zhang, Hansi, Zhang, Ming, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493072/
https://www.ncbi.nlm.nih.gov/pubmed/34630099
http://dx.doi.org/10.3389/fphar.2021.720866