Cargando…

Analysis of Immune Landscape Reveals Prognostic Significance of Cytotoxic CD4(+) T Cells in the Central Region of pMMR CRC

BACKGROUND: Mismatch repair proficient colorectal cancer (pMMR CRC) lacks effective treatments and has a poor prognosis, which can be attributed to the complexity of tumor microenvironment. The coordinated function of immune cells is vital to anti-tumor immunity. However, the spatial characteristics...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Jingwen, Liu, Xiaoyan, Yan, Peian, He, Shangwen, Lin, Yuhao, Huang, Zhiwei, Zhang, Shenyan, Xie, Siyu, Li, Yanfeng, Lu, Xiaofei, Wu, Yingjun, Zhou, Yangshu, Yuan, Juanjuan, Cai, Ting, Zheng, Xiaojun, Ding, Yanqing, Yang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493090/
https://www.ncbi.nlm.nih.gov/pubmed/34631551
http://dx.doi.org/10.3389/fonc.2021.724232