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Analysis of Immune Landscape Reveals Prognostic Significance of Cytotoxic CD4(+) T Cells in the Central Region of pMMR CRC

BACKGROUND: Mismatch repair proficient colorectal cancer (pMMR CRC) lacks effective treatments and has a poor prognosis, which can be attributed to the complexity of tumor microenvironment. The coordinated function of immune cells is vital to anti-tumor immunity. However, the spatial characteristics...

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Detalles Bibliográficos
Autores principales:	Qi, Jingwen, Liu, Xiaoyan, Yan, Peian, He, Shangwen, Lin, Yuhao, Huang, Zhiwei, Zhang, Shenyan, Xie, Siyu, Li, Yanfeng, Lu, Xiaofei, Wu, Yingjun, Zhou, Yangshu, Yuan, Juanjuan, Cai, Ting, Zheng, Xiaojun, Ding, Yanqing, Yang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493090/ https://www.ncbi.nlm.nih.gov/pubmed/34631551 http://dx.doi.org/10.3389/fonc.2021.724232

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