Tempol Reverses the Negative Effects of Morphine on Arterial Blood-Gas Chemistry and Tissue Oxygen Saturation in Freely-Moving Rats

We have reported that pretreatment with the clinically approved superoxide dismutase mimetic, Tempol (4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl), blunts the cardiorespiratory depressant responses elicited by a subsequent injection of fentanyl, in halothane-anesthetized rats. The objective of th...

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Detalles Bibliográficos
Autores principales: Baby, Santhosh M., Discala, Joseph F., Gruber, Ryan, Getsy, Paulina M., Cheng, Feixiong, Damron, Derek S., Lewis, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493249/
https://www.ncbi.nlm.nih.gov/pubmed/34630119
http://dx.doi.org/10.3389/fphar.2021.749084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493249/
https://www.ncbi.nlm.nih.gov/pubmed/34630119
http://dx.doi.org/10.3389/fphar.2021.749084

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