A KDM4-DBC1-SIRT1 Axis Contributes to TGF-b Induced Mesenchymal Transition of Intestinal Epithelial Cells

Intestinal fibrosis is one of the common pathophysiological processes in inflammatory bowel diseases (IBDs). Previously it has been demonstrated that epithelial-mesenchymal transition (EMT) can contribute to the development of intestinal fibrosis. Here we report that conditional ablation of SIRT1, a...

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Detalles Bibliográficos
Autores principales: Chen, Baoyu, Dong, Wenhui, Shao, Tinghui, Miao, Xiulian, Guo, Yan, Liu, Xingyu, Feng, Yifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493255/
https://www.ncbi.nlm.nih.gov/pubmed/34631698
http://dx.doi.org/10.3389/fcell.2021.697614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493255/
https://www.ncbi.nlm.nih.gov/pubmed/34631698
http://dx.doi.org/10.3389/fcell.2021.697614

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