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Association of Regional White Matter Hyperintensities With Longitudinal Alzheimer-Like Pattern of Neurodegeneration in Older Adults

IMPORTANCE: Small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMH), is associated with cognitive decline and risk of clinical Alzheimer disease (AD). One way in which small vessel cerebrovascular disease could contribute to AD is through the promotion of neurodegener...

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Detalles Bibliográficos
Autores principales: Rizvi, Batool, Lao, Patrick J., Chesebro, Anthony G., Dworkin, Jordan D., Amarante, Erica, Beato, Juliet M., Gutierrez, Jose, Zahodne, Laura B., Schupf, Nicole, Manly, Jennifer J., Mayeux, Richard, Brickman, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493439/
https://www.ncbi.nlm.nih.gov/pubmed/34609497
http://dx.doi.org/10.1001/jamanetworkopen.2021.25166