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Association of Regional White Matter Hyperintensities With Longitudinal Alzheimer-Like Pattern of Neurodegeneration in Older Adults
IMPORTANCE: Small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMH), is associated with cognitive decline and risk of clinical Alzheimer disease (AD). One way in which small vessel cerebrovascular disease could contribute to AD is through the promotion of neurodegener...
Autores principales: | Rizvi, Batool, Lao, Patrick J., Chesebro, Anthony G., Dworkin, Jordan D., Amarante, Erica, Beato, Juliet M., Gutierrez, Jose, Zahodne, Laura B., Schupf, Nicole, Manly, Jennifer J., Mayeux, Richard, Brickman, Adam M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493439/ https://www.ncbi.nlm.nih.gov/pubmed/34609497 http://dx.doi.org/10.1001/jamanetworkopen.2021.25166 |
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