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Targeting of myeloid-derived suppressor cells by all-trans retinoic acid as host-directed therapy for human tuberculosis

Conventional anti-tuberculosis (TB) therapies comprise lengthy antibiotic treatment regimens, exacerbated by multi-drug resistant and extensively drug resistant mycobacterial strains. We assessed the ability of all-trans retinoic acid (ATRA), as repurposed compound serving as host-directed therapy (...

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Detalles Bibliográficos
Autores principales: Leukes, Vinzeigh N., Dorhoi, Anca, Malherbe, Stephanus T., Maasdorp, Elizna, Khoury, Justine, McAnda, Shirley, Walzl, Gerhard, du Plessis, Nelita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493473/
https://www.ncbi.nlm.nih.gov/pubmed/33865151
http://dx.doi.org/10.1016/j.cellimm.2021.104359