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Targeting of myeloid-derived suppressor cells by all-trans retinoic acid as host-directed therapy for human tuberculosis
Conventional anti-tuberculosis (TB) therapies comprise lengthy antibiotic treatment regimens, exacerbated by multi-drug resistant and extensively drug resistant mycobacterial strains. We assessed the ability of all-trans retinoic acid (ATRA), as repurposed compound serving as host-directed therapy (...
Autores principales: | Leukes, Vinzeigh N., Dorhoi, Anca, Malherbe, Stephanus T., Maasdorp, Elizna, Khoury, Justine, McAnda, Shirley, Walzl, Gerhard, du Plessis, Nelita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493473/ https://www.ncbi.nlm.nih.gov/pubmed/33865151 http://dx.doi.org/10.1016/j.cellimm.2021.104359 |
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