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Engineering a genome‐reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo

Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome‐reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm‐associated bacterial infections. This strain has a unique genetic code, which hinders gene transfer to...

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Detalles Bibliográficos
Autores principales: Garrido, Victoria, Piñero‐Lambea, Carlos, Rodriguez‐Arce, Irene, Paetzold, Bernhard, Ferrar, Tony, Weber, Marc, Garcia‐Ramallo, Eva, Gallo, Carolina, Collantes, María, Peñuelas, Iván, Serrano, Luis, Grilló, María‐Jesús, Lluch‐Senar, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493563/
https://www.ncbi.nlm.nih.gov/pubmed/34612607
http://dx.doi.org/10.15252/msb.202010145