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Engineering a genome‐reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo
Bacteria present a promising delivery system for treating human diseases. Here, we engineered the genome‐reduced human lung pathogen Mycoplasma pneumoniae as a live biotherapeutic to treat biofilm‐associated bacterial infections. This strain has a unique genetic code, which hinders gene transfer to...
Autores principales: | Garrido, Victoria, Piñero‐Lambea, Carlos, Rodriguez‐Arce, Irene, Paetzold, Bernhard, Ferrar, Tony, Weber, Marc, Garcia‐Ramallo, Eva, Gallo, Carolina, Collantes, María, Peñuelas, Iván, Serrano, Luis, Grilló, María‐Jesús, Lluch‐Senar, María |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493563/ https://www.ncbi.nlm.nih.gov/pubmed/34612607 http://dx.doi.org/10.15252/msb.202010145 |
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