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Lentiviral-mediated ectopic expression of YAP and TAZ in YAP(off) cancer cell lines

Ectopic/overexpression systems are important for studying protein function, but care must be taken to avoid artifacts due to excessively high levels of overexpression. To study the function of YAP/TAZ in YAP/TAZ-deficient (YAP(off)) cancers, we developed a lentiviral system using weak, constitutive...

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Detalles Bibliográficos
Autores principales: Pearson, Joel D., Bremner, Rod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493570/
https://www.ncbi.nlm.nih.gov/pubmed/34632420
http://dx.doi.org/10.1016/j.xpro.2021.100870