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BMI1 is associated with CSF amyloid-β and rates of cognitive decline in Alzheimer’s disease

BACKGROUND: Accumulating evidence suggests that BMI1 confers protective effects against Alzheimer’s disease (AD). However, the mechanism remains elusive. Based on recent pathophysiological evidence, we sought for the first time to identify genetic variants in BMI1 as associated with AD biomarkers, i...

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Detalles Bibliográficos
Autores principales: Kim, Jun Pyo, Kim, Bo-Hyun, Bice, Paula J., Seo, Sang Won, Bennett, David A., Saykin, Andrew J., Nho, Kwangsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493672/
https://www.ncbi.nlm.nih.gov/pubmed/34610832
http://dx.doi.org/10.1186/s13195-021-00906-4