Spontaneous recovery from sunitinib-induced disruption of sarcomere in human iPSC-cardiomyocytes and possible involvement of the Hippo pathway

BACKGROUND: Sunitinib is known to cause cardiotoxicity in clinical settings. However, among sunitinib-treated patients experiencing adverse cardiac events, decreased cardiac function was reportedly reversible in > 50% of the patients. We previously showed that anti-cancer drugs such as sunitinib...

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Detalles Bibliográficos
Autores principales: Matsui, Toshikatsu, Shinozawa, Tadahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493690/
https://www.ncbi.nlm.nih.gov/pubmed/34610839
http://dx.doi.org/10.1186/s40360-021-00527-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493690/
https://www.ncbi.nlm.nih.gov/pubmed/34610839
http://dx.doi.org/10.1186/s40360-021-00527-5

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