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Repertoire analysis of γδ T cells in the chicken enables functional annotation of the genomic region revealing highly variable pan-tissue TCR gamma V gene usage as well as identifying public and private repertoires

BACKGROUND: Despite increasing interest in γδ T cells and their non-classical behaviour, most studies focus on animals with low numbers of circulating γδ T cells, such as mice and humans. Arguably, γδ T cell functions might be more prominent in chickens where these cells form a higher proportion of...

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Detalles Bibliográficos
Autores principales: Dixon, Robert, Preston, Stephen G., Dascalu, Stefan, Flammer, Patrik G., Fiddaman, Steven R., McLoughlin, Kirstie, Boyd, Amy, Volf, Jiri, Rychlik, Ivan, Bonsall, Michael B., Kaspers, Bernd, Smith, Adrian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493715/
https://www.ncbi.nlm.nih.gov/pubmed/34610803
http://dx.doi.org/10.1186/s12864-021-08036-9