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Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints

Several RNA viruses can establish life-long persistent infection in mammalian hosts, but the fate of individual virus-infected cells remains undefined. Here we used Cre recombinase–encoding lymphocytic choriomeningitis virus to establish persistent infection in fluorescent cell fate reporter mice. V...

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Detalles Bibliográficos
Autores principales: Reuther, Peter, Martin, Katrin, Kreutzfeldt, Mario, Ciancaglini, Matias, Geier, Florian, Calabrese, Diego, Merkler, Doron, Pinschewer, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493862/
https://www.ncbi.nlm.nih.gov/pubmed/34398180
http://dx.doi.org/10.1084/jem.20210408