Cargando…
Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints
Several RNA viruses can establish life-long persistent infection in mammalian hosts, but the fate of individual virus-infected cells remains undefined. Here we used Cre recombinase–encoding lymphocytic choriomeningitis virus to establish persistent infection in fluorescent cell fate reporter mice. V...
Autores principales: | Reuther, Peter, Martin, Katrin, Kreutzfeldt, Mario, Ciancaglini, Matias, Geier, Florian, Calabrese, Diego, Merkler, Doron, Pinschewer, Daniel D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493862/ https://www.ncbi.nlm.nih.gov/pubmed/34398180 http://dx.doi.org/10.1084/jem.20210408 |
Ejemplares similares
-
Envelope Exchange for the Generation of Live-Attenuated Arenavirus Vaccines
por: Bergthaler, Andreas, et al.
Publicado: (2006) -
Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infection
por: Steinbach, Karin, et al.
Publicado: (2016) -
Immunological Mechanism of Action and Clinical Profile of Disease-Modifying Treatments in Multiple Sclerosis
por: Du Pasquier, Renaud A., et al.
Publicado: (2014) -
The Janus Kinase Inhibitor Ruxolitinib Prevents Terminal Shock in a Mouse Model of Arenavirus Hemorrhagic Fever
por: Sahin, Mehmet, et al.
Publicado: (2021) -
T Cell-Dependence of Lassa Fever Pathogenesis
por: Flatz, Lukas, et al.
Publicado: (2010)