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Sulfated poly-amido-saccharides (sulPASs) are anticoagulants in vitro and in vivo

Anticoagulant therapeutics are a mainstay of modern surgery and of clotting disorder management such as venous thrombosis, yet performance and supply limitations exist for the most widely used agent – heparin. Herein we report the first synthesis, characterization, and performance of sulfated poly-a...

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Detalles Bibliográficos
Autores principales: Varghese, Maria, Rokosh, Rae S., Haller, Carolyn A., Chin, Stacy L., Chen, Jiaxuan, Dai, Erbin, Xiao, Ruiqing, Chaikof, Elliot L., Grinstaff, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494039/
https://www.ncbi.nlm.nih.gov/pubmed/34703558
http://dx.doi.org/10.1039/d1sc02302k