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Sulfated poly-amido-saccharides (sulPASs) are anticoagulants in vitro and in vivo
Anticoagulant therapeutics are a mainstay of modern surgery and of clotting disorder management such as venous thrombosis, yet performance and supply limitations exist for the most widely used agent – heparin. Herein we report the first synthesis, characterization, and performance of sulfated poly-a...
Autores principales: | Varghese, Maria, Rokosh, Rae S., Haller, Carolyn A., Chin, Stacy L., Chen, Jiaxuan, Dai, Erbin, Xiao, Ruiqing, Chaikof, Elliot L., Grinstaff, Mark W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494039/ https://www.ncbi.nlm.nih.gov/pubmed/34703558 http://dx.doi.org/10.1039/d1sc02302k |
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