Human Three-Finger Protein Lypd6 Is a Negative Modulator of the Cholinergic System in the Brain

Lypd6 is a GPI-tethered protein from the Ly-6/uPAR family expressed in the brain. Lypd6 enhances the Wnt/β-catenin signaling, although its action on nicotinic acetylcholine receptors (nAChRs) have been also proposed. To investigate a cholinergic activity of Lypd6, we studied a recombinant water-solu...

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Detalles Bibliográficos
Autores principales: Kulbatskii, Dmitrii, Shenkarev, Zakhar, Bychkov, Maxim, Loktyushov, Eugene, Shulepko, Mikhail, Koshelev, Sergey, Povarov, Igor, Popov, Alexander, Peigneur, Steve, Chugunov, Anton, Kozlov, Sergey, Sharonova, Irina, Efremov, Roman, Skrebitsky, Vladimir, Tytgat, Jan, Kirpichnikov, Mikhail, Lyukmanova, Ekaterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494132/
https://www.ncbi.nlm.nih.gov/pubmed/34631692
http://dx.doi.org/10.3389/fcell.2021.662227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494132/
https://www.ncbi.nlm.nih.gov/pubmed/34631692
http://dx.doi.org/10.3389/fcell.2021.662227

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