Vertebrate CTF18 and DDX11 essential function in cohesion is bypassed by preventing WAPL-mediated cohesin release

The alternative PCNA loader containing CTF18-DCC1-CTF8 facilitates sister chromatid cohesion (SCC) by poorly defined mechanisms. Here we found that in DT40 cells, CTF18 acts complementarily with the Warsaw breakage syndrome DDX11 helicase in mediating SCC and proliferation. We uncover that the letha...

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Detalles Bibliográficos
Autores principales: Kawasumi, Ryotaro, Abe, Takuya, Psakhye, Ivan, Miyata, Keiji, Hirota, Kouji, Branzei, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494208/
https://www.ncbi.nlm.nih.gov/pubmed/34503989
http://dx.doi.org/10.1101/gad.348581.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494208/
https://www.ncbi.nlm.nih.gov/pubmed/34503989
http://dx.doi.org/10.1101/gad.348581.121

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