Likelihood-based deconvolution of bulk gene expression data using single-cell references

Direct comparison of bulk gene expression profiles is complicated by distinct cell type mixtures in each sample that obscure whether observed differences are actually caused by changes in the expression levels themselves or are simply a result of differing cell type compositions. Single-cell technol...

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Detalles Bibliográficos
Autores principales: Erdmann-Pham, Dan D., Fischer, Jonathan, Hong, Justin, Song, Yun S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494215/
https://www.ncbi.nlm.nih.gov/pubmed/34301624
http://dx.doi.org/10.1101/gr.272344.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494215/
https://www.ncbi.nlm.nih.gov/pubmed/34301624
http://dx.doi.org/10.1101/gr.272344.120

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