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Cancer cell states and emergent properties of the dynamic tumor system

Phenotypic heterogeneity within malignant cells of a tumor is emerging as a key property of tumorigenesis. Recent work using single-cell transcriptomics has led to the identification of distinct cancer cell states across a range of cancer types, but their functional relevance and the advantage that...

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Detalles Bibliográficos
Autores principales: Barkley, Dalia, Rao, Anjali, Pour, Maayan, França, Gustavo S., Yanai, Itai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494223/
https://www.ncbi.nlm.nih.gov/pubmed/34599005
http://dx.doi.org/10.1101/gr.275308.121