Melatonin increases 5-flurouracil-mediated apoptosis of colorectal cancer cells through enhancing oxidative stress and downregulating survivin and XIAP

[Image: see text] Introduction: Colorectal cancer (CRC) is one of the most lethal human malignancies with a global alarming rate of incidence. The development of resistance against common chemotherapeutics such as 5-fluorouracil (5-FU) remains a big burden for CRC therapy. Therefore, we investigated...

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Detalles Bibliográficos
Autores principales: Mihanfar, Ainaz, Yousefi, Bahman, Ghazizadeh Darband, Saber, Sadighparvar, Shirin, Kaviani, Mojtaba, Majidinia, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences (TUOMS Publishing Group) 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494259/
https://www.ncbi.nlm.nih.gov/pubmed/34631487
http://dx.doi.org/10.34172/bi.2021.36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494259/
https://www.ncbi.nlm.nih.gov/pubmed/34631487
http://dx.doi.org/10.34172/bi.2021.36

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