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Nobiletin, a hexamethoxyflavonoid from citrus pomace, attenuates G1 cell cycle arrest and apoptosis in hypoxia-induced human trophoblast cells of JEG-3 and BeWo via regulating the p53 signaling pathway

BACKGROUND: Hypoxia is associated with abnormal cell apoptosis in trophoblast cells, which causes fetal growth restriction and related placental pathologies. Few effective methods for the prevention and treatment of placenta-related diseases exist. Natural products and functional foods have always b...

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Detalles Bibliográficos
Autores principales: Zhang, Mengling, Liu, Jian, Zhang, Rui, Liang, Zengenni, Ding, Shenghua, Yu, Huanling, Shan, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Open Academia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494266/
https://www.ncbi.nlm.nih.gov/pubmed/34650395
http://dx.doi.org/10.29219/fnr.v65.5649