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Relief of ParB autoinhibition by parS DNA catalysis and recycling of ParB by CTP hydrolysis promote bacterial centromere assembly

Three-component ParABS systems are widely distributed factors for plasmid partitioning and chromosome segregation in bacteria. ParB acts as adaptor protein between the 16–base pair centromeric parS DNA sequences and the DNA segregation proteins ParA and Smc (structural maintenance of chromosomes). U...

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Detalles Bibliográficos
Autores principales: Antar, Hammam, Soh, Young-Min, Zamuner, Stefano, Bock, Florian P., Anchimiuk, Anna, Rios, Paolo De Los, Gruber, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494293/
https://www.ncbi.nlm.nih.gov/pubmed/34613769
http://dx.doi.org/10.1126/sciadv.abj2854