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NLRP3 Inflammasome Activation of Mast Cells by Estrogen via the Nuclear-Initiated Signaling Pathway Contributes to the Development of Endometriosis

Endometriosis is an estrogen-dependent gynecological disease. The pathogenesis of endometriosis remains controversial, although it is generally accepted that the inflammatory immune response plays a crucial role in this process. Mast cells (MCs) are multifunctional innate immune cells that accumulat...

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Detalles Bibliográficos
Autores principales: Guo, Xinyue, Xu, Xinxin, Li, Tiantian, Yu, Qin, Wang, Jianzhang, Chen, Yichen, Ding, Shaojie, Zhu, Libo, Zou, Gen, Zhang, Xinmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494307/
https://www.ncbi.nlm.nih.gov/pubmed/34630429
http://dx.doi.org/10.3389/fimmu.2021.749979