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Interplay of Trypanosome Lytic Factor and innate immune cells in the resolution of cutaneous Leishmania infection

Trypanosome Lytic Factor (TLF) is a primate-specific high-density lipoprotein (HDL) complex that, through the cation channel-forming protein apolipoprotein L-1 (APOL1), provides innate immunity to select kinetoplastid parasites. The immunoprotective effects of TLF have been extensively investigated...

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Detalles Bibliográficos
Autores principales: Pant, Jyoti, Samanovic, Marie, Nelson, Maria T., Keceli, Mert K., Verdi, Joseph, Beverley, Stephen M., Raper, Jayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494325/
https://www.ncbi.nlm.nih.gov/pubmed/34559857
http://dx.doi.org/10.1371/journal.ppat.1008768