In silico identification of natural product inhibitors against Octamer-binding transcription factor 4 (Oct4) to impede the mechanism of glioma stem cells

Octamer-binding transcription factor 4 (Oct4) is a core regulator in the retention of stemness, invasive, and self-renewal properties in glioma initiating cells (GSCs) and its overexpression inhibits the differentiation of glioma cells promoting tumor cell proliferation. The Pit-Oct-Unc (POU) domain...

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Detalles Bibliográficos
Autores principales: Nayak, Chirasmita, Singh, Sanjeev Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494328/
https://www.ncbi.nlm.nih.gov/pubmed/34613998
http://dx.doi.org/10.1371/journal.pone.0255803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494328/
https://www.ncbi.nlm.nih.gov/pubmed/34613998
http://dx.doi.org/10.1371/journal.pone.0255803

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