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The role of nuclear organization in trans-splicing based expression of heat shock protein 90 in Giardia lamblia
Hsp90 gene of G. lamblia has a split nature comprising two ORFs separated by 777 kb on chromosome 5. The ORFs of the split gene on chromosome 5 undergo transcription to generate independent pre-mRNAs that join by a unique trans-splicing reaction that remains partially understood. The canonical cis-a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494341/ https://www.ncbi.nlm.nih.gov/pubmed/34559805 http://dx.doi.org/10.1371/journal.pntd.0009810 |