Interferon b drives intestinal regeneration after radiation

The cGAS-STING cytosolic DNA sensing pathway is critical for host defense. Here, we report that cGAS-STING–dependent type 1 interferon (IFN) response drives intestinal regeneration and animal recovery from radiation injury. STING deficiency has no effect on radiation-induced DNA damage or crypt apop...

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Detalles Bibliográficos
Autores principales: Leibowitz, Brian J., Zhao, Guangyi, Wei, Liang, Ruan, Hang, Epperly, Michael, Chen, Lujia, Lu, Xinghua, Greenberger, Joel S., Zhang, Lin, Yu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494436/
https://www.ncbi.nlm.nih.gov/pubmed/34613772
http://dx.doi.org/10.1126/sciadv.abi5253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494436/
https://www.ncbi.nlm.nih.gov/pubmed/34613772
http://dx.doi.org/10.1126/sciadv.abi5253

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