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Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex

Whether there exists a common signaling mechanism that assembles all glutamatergic synapses is unknown. We show here that knocking out Prickle1 and Prickle2 reduced the formation of the PSD-95–positive glutamatergic synapses in the hippocampus and medial prefrontal cortex in postnatal development by...

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Detalles Bibliográficos
Autores principales: Ban, Yue, Yu, Ting, Feng, Bo, Lorenz, Charlotte, Wang, Xiaojia, Baker, Clayton, Zou, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494439/
https://www.ncbi.nlm.nih.gov/pubmed/34613779
http://dx.doi.org/10.1126/sciadv.abh2974