Fibrin gel enhances the antitumor effects of chimeric antigen receptor T cells in glioblastoma

Regional delivery of chimeric antigen receptor (CAR) T cells in glioblastoma represents a rational therapeutic approach as an alternative to intravenous administration to avoid the blood-brain barrier impediment. Here, we developed a fibrin gel that accommodates CAR-T cell loading and promotes their...

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Detalles Bibliográficos
Autores principales: Ogunnaike, Edikan A., Valdivia, Alain, Yazdimamaghani, Mostafa, Leon, Ernesto, Nandi, Seema, Hudson, Hannah, Du, Hongwei, Khagi, Simon, Gu, Zhen, Savoldo, Barbara, Ligler, Frances S., Hingtgen, Shawn, Dotti, Gianpietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494441/
https://www.ncbi.nlm.nih.gov/pubmed/34613775
http://dx.doi.org/10.1126/sciadv.abg5841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494441/
https://www.ncbi.nlm.nih.gov/pubmed/34613775
http://dx.doi.org/10.1126/sciadv.abg5841

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