Targeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases

Neurons within the tumor microenvironment promote cancer progression; thus, their local targeting has potential clinical benefits. We designed PEGylated lipid nanoparticles loaded with a non-opioid analgesic, bupivacaine, to target neurons within breast cancer tumors and suppress nerve-to-cancer cro...

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Detalles Bibliográficos
Autores principales: Kaduri, Maya, Sela, Mor, Kagan, Shaked, Poley, Maria, Abumanhal-Masarweh, Hanan, Mora-Raimundo, Patricia, Ouro, Alberto, Dahan, Nitsan, Hershkovitz, Dov, Shklover, Jeny, Shainsky-Roitman, Janna, Buganim, Yosef, Schroeder, Avi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494443/
https://www.ncbi.nlm.nih.gov/pubmed/34613777
http://dx.doi.org/10.1126/sciadv.abj5435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494443/
https://www.ncbi.nlm.nih.gov/pubmed/34613777
http://dx.doi.org/10.1126/sciadv.abj5435

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