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Targeting neurons in the tumor microenvironment with bupivacaine nanoparticles reduces breast cancer progression and metastases
Neurons within the tumor microenvironment promote cancer progression; thus, their local targeting has potential clinical benefits. We designed PEGylated lipid nanoparticles loaded with a non-opioid analgesic, bupivacaine, to target neurons within breast cancer tumors and suppress nerve-to-cancer cro...
Autores principales: | Kaduri, Maya, Sela, Mor, Kagan, Shaked, Poley, Maria, Abumanhal-Masarweh, Hanan, Mora-Raimundo, Patricia, Ouro, Alberto, Dahan, Nitsan, Hershkovitz, Dov, Shklover, Jeny, Shainsky-Roitman, Janna, Buganim, Yosef, Schroeder, Avi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494443/ https://www.ncbi.nlm.nih.gov/pubmed/34613777 http://dx.doi.org/10.1126/sciadv.abj5435 |
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