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Effect of Dapagliflozin on the Functioning of Rat Liver Mitochondria In Vitro

We studied the effect of a new hypoglycemic compound dapagliflozin on the functioning of rat liver mitochondria. Dapagliflozin in concentrations of 10-20 μM had no effect on the parameters of respiration and oxidative phosphorylation of rat liver mitochondria. Increasing dapagliflozin concentration...

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Detalles Bibliográficos
Autores principales: Belosludtseva, N. V., Starinets, V. S., Belosludtsev, K. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494602/
https://www.ncbi.nlm.nih.gov/pubmed/34617185
http://dx.doi.org/10.1007/s10517-021-05277-2