Cargando…

Effect of Dapagliflozin on the Functioning of Rat Liver Mitochondria In Vitro

We studied the effect of a new hypoglycemic compound dapagliflozin on the functioning of rat liver mitochondria. Dapagliflozin in concentrations of 10-20 μM had no effect on the parameters of respiration and oxidative phosphorylation of rat liver mitochondria. Increasing dapagliflozin concentration...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belosludtseva, N. V., Starinets, V. S., Belosludtsev, K. N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494602/ https://www.ncbi.nlm.nih.gov/pubmed/34617185 http://dx.doi.org/10.1007/s10517-021-05277-2

Ejemplares similares

The Effect of Deflazacort Treatment on the Functioning of Skeletal Muscle Mitochondria in Duchenne Muscular Dystrophy
por: Dubinin, Mikhail V., et al.
Publicado: (2020)

Transport of Ca(2+) and Ca(2+)-Dependent Permeability Transition in Rat Liver Mitochondria under the Streptozotocin-Induced Type I Diabetes
por: Belosludtsev, Konstantin N., et al.
Publicado: (2019)

The Effect of S-15176 Difumarate Salt on Ultrastructure and Functions of Liver Mitochondria of C57BL/6 Mice with Streptozotocin/High-Fat Diet-Induced Type 2 Diabetes
por: Belosludtseva, Natalia V., et al.
Publicado: (2020)

Transport of Ca(2+) and Ca(2+)-Dependent Permeability Transition in the Liver and Heart Mitochondria of Rats with Different Tolerance to Acute Hypoxia
por: Belosludtsev, Konstantin N., et al.
Publicado: (2020)

Effect of the Non-Immunosuppressive MPT Pore Inhibitor Alisporivir on the Functioning of Heart Mitochondria in Dystrophin-Deficient mdx Mice
por: Dubinin, Mikhail V., et al.
Publicado: (2021)

The Effect of Uridine on the State of Skeletal Muscles and the Functioning of Mitochondria in Duchenne Dystrophy
por: Dubinin, Mikhail V., et al.
Publicado: (2022)

BK(Ca) Activator NS1619 Improves the Structure and Function of Skeletal Muscle Mitochondria in Duchenne Dystrophy
por: Dubinin, Mikhail V., et al.
Publicado: (2022)

Effect of Chronic Treatment with Uridine on Cardiac Mitochondrial Dysfunction in the C57BL/6 Mouse Model of High-Fat Diet–Streptozotocin-Induced Diabetes
por: Belosludtseva, Natalia V., et al.
Publicado: (2022)

Alisporivir Normalizes Mitochondrial Function of Primary Mouse Lung Endothelial Cells Under Conditions of Hyperglycemia
por: Starinets, Vlada S., et al.
Publicado: (2022)

Alisporivir Improves Mitochondrial Function in Skeletal Muscle of mdx Mice but Suppresses Mitochondrial Dynamics and Biogenesis
por: Dubinin, Mikhail V., et al.
Publicado: (2021)

Alterations in Mitochondrial Morphology and Quality Control in Primary Mouse Lung Microvascular Endothelial Cells and Human Dermal Fibroblasts under Hyperglycemic Conditions
por: Belosludtseva, Natalia V., et al.
Publicado: (2023)

S-15176 Difumarate Salt Can Impair Mitochondrial Function through Inhibition of the Respiratory Complex III and Permeabilization of the Inner Mitochondrial Membrane
por: Belosludtseva, Natalia V., et al.
Publicado: (2022)

Effect of the MPT Pore Inhibitor Alisporivir on the Development of Mitochondrial Dysfunction in the Heart Tissue of Diabetic Mice
por: Belosludtseva, Natalia V., et al.
Publicado: (2021)

The Short-Term Opening of Cyclosporin A-Independent Palmitate/Sr(2+)-Induced Pore Can Underlie Ion Efflux in the Oscillatory Mode of Functioning of Rat Liver Mitochondria
por: Belosludtseva, Natalia V., et al.
Publicado: (2022)

Alisporivir Treatment Alleviates Mitochondrial Dysfunction in the Skeletal Muscles of C57BL/6NCrl Mice with High-Fat Diet/Streptozotocin-Induced Diabetes Mellitus
por: Belosludtsev, Konstantin N., et al.
Publicado: (2021)

Structural and Dynamic Features of Liver Mitochondria and Mitophagy in Rats with Hyperthyroidism
por: Venediktova, Natalya, et al.
Publicado: (2022)

Diabetes Mellitus, Mitochondrial Dysfunction and Ca(2+)-Dependent Permeability Transition Pore
por: Belosludtsev, Konstantin N., et al.
Publicado: (2020)

Pharmacological and Genetic Suppression of VDAC1 Alleviates the Development of Mitochondrial Dysfunction in Endothelial and Fibroblast Cell Cultures upon Hyperglycemic Conditions
por: Belosludtsev, Konstantin N., et al.
Publicado: (2023)

Functional State of Rat Heart Mitochondria in Experimental Hyperthyroidism
por: Venediktova, Natalya, et al.
Publicado: (2021)

Effect of Thyroxine on the Structural and Dynamic Features of Cardiac Mitochondria and Mitophagy in Rats
por: Venediktova, Natalya, et al.
Publicado: (2023)

SEDIMENTATION PROPERTIES OF RAT LIVER MITOCHONDRIA : Effects of Cortisone Treatment
por: Loeb, John N., et al.
Publicado: (1970)

Conjugation of Triterpenic Acids of Ursane and Oleanane Types with Mitochondria-Targeting Cation F16 Synergistically Enhanced Their Cytotoxicity against Tumor Cells
por: Dubinin, Mikhail V., et al.
Publicado: (2023)

EFFECTS OF CORTISONE ADMINISTRATION ON RAT LIVER MITOCHONDRIA : Support for the Concept of Mitochondrial Fusion
por: Kimberg, Daniel V., et al.
Publicado: (1972)

EFFECTS OF CORTISONE ON RAT LIVER MITOCHONDRIA
por: Lowe, Charles Upton, et al.
Publicado: (1955)

Effect of Modified Levopimaric Acid Diene Adducts on Mitochondrial and Liposome Membranes
por: Dubinin, Mikhail V., et al.
Publicado: (2022)

In Vitro Toxicity of Epigallocatechin Gallate in Rat Liver Mitochondria and Hepatocytes
por: Kucera, Otto, et al.
Publicado: (2015)

Conjugation of Natural Triterpenic Acids with Delocalized Lipophilic Cations: Selective Targeting Cancer Cell Mitochondria
por: Spivak, Anna Yu., et al.
Publicado: (2021)

Evaluation of toxic effects of dapagliflozin on reproductive system in diabetic rats
por: ULUS KARACA, Bahar, et al.
Publicado: (2022)

Dapagliflozin-Induced Acute-on-Chronic Liver Injury
por: Levine, Joshua A., et al.
Publicado: (2016)

THE MORPHOLOGY OF THE SWELLING PROCESS IN RAT LIVER MITOCHONDRIA
por: Myron, D. R., et al.
Publicado: (1971)

LOCALIZATION OF THE ENZYMES OF KETOGENESIS IN RAT LIVER MITOCHONDRIA
por: Chapman, M. John, et al.
Publicado: (1973)

A Comparison of the Pharmacokinetics and Safety of Dapagliflozin Formate, an Ester Prodrug of Dapagliflozin, to Dapagliflozin Propanediol Monohydrate in Healthy Subjects
por: Kim, Hyun Chul, et al.
Publicado: (2023)

Germinal proto-mitochondria from rat liver
por: Vekshin, Nikolai, et al.
Publicado: (2019)

Effect of dapagliflozin according to baseline systolic blood pressure in the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure trial (DAPA-HF)
por: Serenelli, Matteo, et al.
Publicado: (2020)

Protein profiling and functional analysis of liver mitochondria from rats with nonalcoholic steatohepatitis
por: You, Yanting, et al.
Publicado: (2017)

THE EFFECTS OF OSMOTIC LYSIS ON THE OXIDATIVE PHOSPHORYLATION AND COMPARTMENTATION OF RAT LIVER MITOCHONDRIA
por: Caplan, Arnold I., et al.
Publicado: (1968)

The effect of Dapagliflozin on renal functions in hospitalized patients with Acute Heart Failure
por: Gilani, Syedah Fauzia Fatima, et al.
Publicado: (2023)

STUDY OF MITOCHONDRIA IN RAT LIVER : Quantitative Electron Microscopy
por: Bahr, Gunter F., et al.
Publicado: (1962)

PREPARATION OF ISOLATED RAT LIVER MITOCHONDRIA FOR ELECTRON MICROSCOPY
por: Butler, W. H., et al.
Publicado: (1970)

The Swelling of Rat Liver Mitochondria by Thyroxine and its Reversal
por: Lehninger, Albert L., et al.
Publicado: (1959)

Cannot write session to /tmp/vufind_sessions/sess_9piq92vv8teokhc78iqq10cso0