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Single-cell epigenomics reveals mechanisms of human cortical development

During mammalian development, differences in chromatin state coincide with cellular differentiation and reflect changes in the gene regulatory landscape(1). In the developing brain, cell fate specification and topographic identity are important for defining cell identity(2) and confer selective vuln...

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Detalles Bibliográficos
Autores principales: Ziffra, Ryan S., Kim, Chang N., Ross, Jayden M., Wilfert, Amy, Turner, Tychele N., Haeussler, Maximilian, Casella, Alex M., Przytycki, Pawel F., Keough, Kathleen C., Shin, David, Bogdanoff, Derek, Kreimer, Anat, Pollard, Katherine S., Ament, Seth A., Eichler, Evan E., Ahituv, Nadav, Nowakowski, Tomasz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494642/
https://www.ncbi.nlm.nih.gov/pubmed/34616060
http://dx.doi.org/10.1038/s41586-021-03209-8