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Diabetes concomitant to aortic stenosis is associated with increased expression of NF-κB and more pronounced valve calcification

AIMS/HYPOTHESIS: Type 2 diabetes has been demonstrated to predispose to aortic valve calcification. We investigated whether type 2 diabetes concomitant to aortic stenosis (AS) enhances valvular inflammation and coagulation activation via upregulated expression of NF-κB, with subsequent increased exp...

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Detalles Bibliográficos
Autores principales: Kopytek, Magdalena, Mazur, Piotr, Ząbczyk, Michał, Undas, Anetta, Natorska, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494674/
https://www.ncbi.nlm.nih.gov/pubmed/34494136
http://dx.doi.org/10.1007/s00125-021-05545-w