Eliapixant is a selective P2X3 receptor antagonist for the treatment of disorders associated with hypersensitive nerve fibers

ATP-dependent P2X3 receptors play a crucial role in the sensitization of nerve fibers and pathological pain pathways. They are also involved in pathways triggering cough and may contribute to the pathophysiology of endometriosis and overactive bladder. However, despite the strong therapeutic rationa...

Descripción completa

Detalles Bibliográficos
Autores principales: Davenport, Adam J., Neagoe, Ioana, Bräuer, Nico, Koch, Markus, Rotgeri, Andrea, Nagel, Jens, Laux-Biehlmann, Alexis, Machet, Frederic, Coelho, Anne-Marie, Boyce, Susan, Carty, Nikisha, Gemkow, Mark J., Hess, Stephen D., Zollner, Thomas M., Fischer, Oliver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494816/
https://www.ncbi.nlm.nih.gov/pubmed/34615939
http://dx.doi.org/10.1038/s41598-021-99177-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494816/
https://www.ncbi.nlm.nih.gov/pubmed/34615939
http://dx.doi.org/10.1038/s41598-021-99177-0

Ejemplares similares