Genetic effects on longitudinal cognitive decline during the early stages of Alzheimer’s disease

Cognitive decline in early-stage Alzheimer’s disease (AD) may depend on genetic variability. In the Swedish BioFINDER study, we used polygenic scores (PGS) (for AD, intelligence, and educational attainment) to predict longitudinal cognitive change (measured by mini-mental state examination (MMSE) [p...

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Detalles Bibliográficos
Autores principales: Kumar, Atul, Shoai, Maryam, Palmqvist, Sebastian, Stomrud, Erik, Hardy, John, Mattsson-Carlgren, Niklas, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494841/
https://www.ncbi.nlm.nih.gov/pubmed/34615922
http://dx.doi.org/10.1038/s41598-021-99310-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494841/
https://www.ncbi.nlm.nih.gov/pubmed/34615922
http://dx.doi.org/10.1038/s41598-021-99310-z

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