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Cytosolic protein delivery using pH-responsive, charge-reversible lipid nanoparticles
Although proteins have attractive features as biopharmaceuticals, the difficulty in delivering them into the cell interior limits their applicability. Lipid nanoparticles (LNPs) are a promising class of delivery vehicles. When designing a protein delivery system based on LNPs, the major challenges i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494842/ https://www.ncbi.nlm.nih.gov/pubmed/34615928 http://dx.doi.org/10.1038/s41598-021-99180-5 |