Cargando…

Proteomics analysis identifies PEA-15 as an endosomal phosphoprotein that regulates α5β1 integrin endocytosis

Endosomal trafficking of cell surface receptors is essential to their function. Integrins are transmembrane receptors that integrate adhesion to the extracellular matrix with engagement of the cytoskeleton. Ligated integrins mediate diverse signals that regulate matrix assembly, cell survival, cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Caliva, Maisel J., Yang, Won Seok, Young-Robbins, Shirley, Zhou, Ming, Yoon, Hana, Matter, Michelle L., Grimes, Mark L., Conrads, Thomas, Ramos, Joe William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494857/
https://www.ncbi.nlm.nih.gov/pubmed/34615962
http://dx.doi.org/10.1038/s41598-021-99348-z