Activators of alpha synuclein expression identified by reporter cell line-based high throughput drug screen

Multiplications, mutations and dysregulation of the alpha synuclein gene (SNCA) are associated with the demise of dopaminergic neurons and are considered to play important roles in the pathogenesis of familial and sporadic forms of Parkinson’s disease. Regulation of SNCA expression might thus be an...

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Detalles Bibliográficos
Autores principales: Stahl, Fabian, Denner, Philip, Piston, Dominik, Evert, Bernd O., de Boni, Laura, Schmitt, Ina, Breuer, Peter, Wüllner, Ullrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494889/
https://www.ncbi.nlm.nih.gov/pubmed/34615900
http://dx.doi.org/10.1038/s41598-021-98841-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494889/
https://www.ncbi.nlm.nih.gov/pubmed/34615900
http://dx.doi.org/10.1038/s41598-021-98841-9

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