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miR-27b antagonizes BMP signaling in early differentiation of human induced pluripotent stem cells

Human induced pluripotent stem (hiPS) cells are feasible materials for studying the biological mechanisms underlying human embryogenesis. In early embryogenesis, definitive endoderm and mesoderm are differentiated from their common precursor, mesendoderm. Bone morphogenetic protein (BMP) signaling i...

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Detalles Bibliográficos
Autores principales: Lim, Jaeeun, Sakai, Eiko, Sakurai, Fuminori, Mizuguchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494899/
https://www.ncbi.nlm.nih.gov/pubmed/34615950
http://dx.doi.org/10.1038/s41598-021-99403-9