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Screening for Susceptibility-Related Biomarkers of Diclofenac-Induced Liver Injury in Rats Using Metabolomics

Early identification of individuals susceptible to idiosyncratic drug-induced liver injury (IDILI) is a challenging unmet demand. Diclofenac, one of the most widely available over-the-counter drugs for pain management worldwide, may induce liver dysfunction, acute liver failure, and death. Herein, w...

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Detalles Bibliográficos
Autores principales: Tu, Can, Gao, Yuan, Song, Di, Niu, Ming, Ma, Run-ran, Zhou, Ming-xi, He, Xian, Xiao, Xiao-he, Wang, Jia-bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8494976/
https://www.ncbi.nlm.nih.gov/pubmed/34630079
http://dx.doi.org/10.3389/fphar.2021.693928